کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4001228 | 1259401 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Current status of cytotoxic chemotherapy in patients with metastatic prostate cancer
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
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چکیده انگلیسی
Despite efforts at early detection with prostate specific antigen-based screening, more than 25,000 patients in the United States will die this year of metastatic prostate cancer. As a consequence both of screening and increased use of androgen deprivation therapy, patients commonly present with low volume, asymptomatic, metastatic disease. Over the past 2 decades chemotherapy for advanced prostate cancer has evolved from a frightful, toxic experience to one that frequently provides clinically meaningful palliation and a modest, but real survival benefit. With the establishment of docetaxel-based chemotherapy as initial therapy, efforts are underway to evaluate the role of second-line systemic therapy options.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Urologic Oncology: Seminars and Original Investigations - Volume 26, Issue 4, JulyâAugust 2008, Pages 426-429
Journal: Urologic Oncology: Seminars and Original Investigations - Volume 26, Issue 4, JulyâAugust 2008, Pages 426-429
نویسندگان
Robert M.D., F.A.C.P.,