کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4054711 1265534 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anabolic androgenic steroids reverse the beneficial effect of exercise on tendon biomechanics: An experimental study
ترجمه فارسی عنوان
استروئیدهای آندروژنی آنابولیک اثرات سودمند ورزش بر روی بیومکانیک تاندون را معکوس می کند: یک مطالعه تجربی
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی

BackgroundThe effect of anabolic androgenic steroids on tendons has not yet been fully elucidated. Aim of the present study was the evaluation of the impact of anabolic androgenic steroids on the biomechanical and histological characteristics of Achilles tendons.MethodsTwenty-four male Wistar rats were randomized into four groups with exercise and anabolic steroids (nandrolone decanoate) serving as variables. Protocol duration was 12 weeks. Following euthanasia, tendons’ biomechanical properties were tested with the use of a modified clamping configuration. Histological examination with light and electron microscopy were also performed.ResultsIn the group of anabolic steroids and exercise the lowest fracture stress values were observed, while in the exercise group the highest ones. Histological examination by light and electron microscopy revealed areas of collagen dysplasia and an increased epitendon in the groups receiving anabolic steroids and exercise.ConclusionsThese findings suggest that anabolic androgenic steroids reverse the beneficial effect of exercise, thus resulting in inferior maximal stress values.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Foot and Ankle Surgery - Volume 20, Issue 2, June 2014, Pages 94–99
نویسندگان
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