کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4059948 1603980 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lower Total Knee Arthroplasty Revision Risk Associated With Bisphosphonate Use, Even in Patients With Normal Bone Density
ترجمه فارسی عنوان
کاهش خطر بروز آرتروپلاستی کمر درد همراه با استفاده از بیس فسفونات حتی در بیماران با تراکم استخوان طبیعی
کلمات کلیدی
زانو کامل بیسفسفونات ها، تجدید نظر، تراکم استخوان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی

BackgroundBisphosphonates (BPs) are associated with lower total knee arthroplasty (TKA) revision risk, but the effect of bone mineral density has not been evaluated.MethodsA cohort of 34,116 primary TKA patients was evaluated with revision surgery and periprosthetic fractures as end points. BP usage was the exposure of interest. Bone quality (normal, osteopenia, and osteoporosis) and patient age (< 65 vs ≥ 65 years) were evaluated as effect modifiers of risk estimates.ResultsOf the patients, 19.6% were BP users. In BP users, 0.5% underwent an aseptic revision; and 0.6%, a periprosthetic fracture. In non-BP users, 1.6% underwent aseptic revision; and 0.1%, a periprosthetic fracture.ConclusionBisphosphonate use was associated with lower risk of revision in all bone quality categories in those older than 65 years. The risk of periprosthetic fractures was higher for patients on BP.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 31, Issue 2, February 2016, Pages 537–541
نویسندگان
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