کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4128297 | 1270918 | 2014 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Réseau de relecture des tumeurs pédiatriques du système nerveux central par le Groupe d'étude de neuropathologie oncologique pédiatrique (GENOP)
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
آسیبشناسی و فناوری پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Réseau de relecture des tumeurs pédiatriques du système nerveux central par le Groupe d'étude de neuropathologie oncologique pédiatrique (GENOP) Réseau de relecture des tumeurs pédiatriques du système nerveux central par le Groupe d'étude de neuropathologie oncologique pédiatrique (GENOP)](/preview/png/4128297.png)
چکیده انگلیسی
Diagnosis of paediatric tumours of the central nervous system is often difficult because WHO classification criteria are mainly defined for adults tumours and do not always apply to their paediatric counterparts. These tumours are rare (400 cases/year among more than 50 pathological subtypes per year in France). Pathological diagnosis may be a challenge for a general pathologist with a too low number of paediatric cases in his recruitment. Hence, a reference group of paediatric neuropathologists was formed (GENOP) on the behalf of the comité “Tumeurs Cérébrales” de la Société Française de lutte contre les Cancers de l'Enfant. This network is supported by the Institut National du Cancer (INCa). GENOP aim is to structure a centralised review of paediatric central nervous system tumours in order to harmonise neuropathological diagnosis at the national level and enhance patients care. Cases assessed during the last 3 years led GENOP to better identify tumours subtypes for which there is a diagnostic challenge. A set of immunohistochemical or molecular specialised techniques was developed, leading to an increased diagnostic accuracy. It allowed a better distinction between diffuse and circumscribed glioma, a better recognition of glioneuronal differentiation and a better subtyping of embryonal tumours such as medulloblastomas. Inter-observer agreement varied according to the tumour subtypes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annales de Pathologie - Volume 34, Issue 1, February 2014, Pages 74-86
Journal: Annales de Pathologie - Volume 34, Issue 1, February 2014, Pages 74-86
نویسندگان
David Meyronet, Karen Silva, Dominique Figarella-Branger, Catherine Godfraind, Marie-Bernadette Delisle, Claude-Alain Maurage, Catherine Miquel, Pascale Varlet, Jean-Claude Gentet, Anne-Isabelle-Bertozzi Salamon, Alexandre Vasiljevic, Anne Jouvet,