کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4138576 | 1272157 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Atypical fibroxanthoma: a selective review
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
آسیبشناسی و فناوری پزشکی
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چکیده انگلیسی
The head and neck area has disproportionate number of cutaneous tumors given the surface area, as compared with the rest of the body. Many of the tumors are related to chronic actinic damage and the most common by far are squamous and basal cell carcinomas. Atypical fibroxanthoma refers to a group of usually indolent cutaneous tumors that occur in older adults and are characterized histologically by a population of fusiform, epithelioid, and pleomorphic cells, numerous cells in mitosis, and intracytoplasmic lipidization in some cells. Numerous histologic variants have been described, including a clear-cell, desmoplastic or keloidal, granular, angiomatoid, hemosiderotic, and myxoid, among others. These tumors have a mesenchymal immunophenotype. Some authors believe that atypical fibroxanthoma is a dedifferentiated variant of squamous cell carcinoma. We present a review of this particular neoplasm with special emphasis on the histomorphology, subtypes, immunophenotypic profile, and discussion of differential diagnosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Diagnostic Pathology - Volume 30, Issue 1, February 2013, Pages 4-12
Journal: Seminars in Diagnostic Pathology - Volume 30, Issue 1, February 2013, Pages 4-12
نویسندگان
Alejandro A. MD, Daniel J. MD,