Involvement of Sphingosine‐1‐Phosphate/RhoA/Rho‐Kinase Signaling Pathway in Corporal Fibrosis Following Cavernous Nerve Injury in Male Rats

Our data suggest that S1P and RhoA/ROCK1 signaling may be involved in corporal fibrosis associated with loss of smooth muscle through coordination with TGF‐β1 after CN injury. Cho MC, Park K, Chai JS, Lee SH, Kim SW, and Paick J‐S. Involvement of sphingosine‐1‐phosphate/RhoA/Rho‐kinase signaling pathway in corporal fibrosis following cavernous nerve injury in male rats. J Sex Med 2011;8:712-721.