Keywords: گیرنده S1P; Sphingosine-1-phosphate; Sphingosine kinase; Estradiol; Breast cancer; FTY720/Fingolimod; ERα; estrogen receptor α; EGFR; epidermal growth factor receptor; ERE; estrogen response element; ERK; extracellular signal regulated kinase; E2; 17β-estradiol; H
مقالات ISI گیرنده S1P (ترجمه نشده)
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Keywords: گیرنده S1P; apo; apolipoprotein; HDL; high-density lipoprotein; HNF-1α,4α; hepatocyte nuclear factor-1α,4α; LRH-1; liver receptor homolog-1; Foxa2; forkhead box A2; PAF; platelet activating factor; LXR; liver X receptor; RXR; retinoid X receptor; FXR; farnesoid X
Sphingosine-1-phosphate mediates the therapeutic effects of bone marrow mesenchymal stem cell-derived microvesicles on articular cartilage defect
Keywords: گیرنده S1P; MVs; microvesicles; MSCs; mesenchymal stem cells; S1P; sphingosine-1-phosphate; S1PR; S1P receptor; IL-1β; interleukin 1 beta; GFP; green fluorescent protein; TEM; transmission electron microscopy; PBS; phosphate buffered saline; FBS; fetal bovine serum;
Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1
Keywords: گیرنده S1P; Angiotensin II; Vascular smooth muscle cell (VSMC); Sphingosine-1-phosphate receptor (S1PR); APE/Ref-1; Vascular neointima; DCF-DA; 6-carboxy-2â²,7â²-dichlorofluoroscein diacetate; Ang II; angiotensin II; AT; Ang II receptor; APE/Ref-1; apurinic/apyrimi
A benzo[b]thiophene-based selective type 4 S1P receptor agonist
Keywords: گیرنده S1P; Sphingosine-1-phosphate; S1P receptor; S1PR4; S1P4; Selective agonist;
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: گیرنده S1P; AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3
Keywords: گیرنده S1P; Endothelial nitric oxide synthesis; Nitric oxide; Sphingosine 1-phosphate; S1P receptor; AUY954; FTY720P;
Pharmacokinetics of H002, a novel S1PR1 modulator, and its metabolites in rat blood using liquid chromatography-tandem mass spectrometry
Keywords: گیرنده S1P; S1P receptor; S1PR1 modulator; Sphingosine-1-phosphate; S1P analogue; Metabolite; LC-MS/MS; Pharmacokinetics; Periphery blood lymphocyte;
FTY720 attenuates hypoxia–reoxygenation-induced apoptosis in cardiomyocytes
Keywords: گیرنده S1P; H9C2 cardiomyocytes; FTY720; S1P receptor; Hypoxia/reoxygenation
Role of Ca2+-dependent and Ca2+-sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro
Keywords: گیرنده S1P; sphingosine 1-phosphate; S1P; S1P receptor 2; porcine retinal arterioles; protein kinase C; vasoconstriction; RBF; retinal blood flow; S1P; sphingosine 1-phosphate; S1PR; S1P receptor; ROCK; rho-associated coiled-coil-forming protein kinase; PKC; protein
Research ArticleSphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis
Keywords: گیرنده S1P; S1P; sphingosine-1-phosphate; SphK; sphingosine kinase; S1PR; S1P receptor; VEGF; vascular endothelial growth factor; HSC; hepatic stellate cells; Ang1; angiopoietin 1; SKI; 2-(p-hydroxyanilino)-4-(p-chloro-phenyl)thiazole; BDL; bile duct ligation; HPLC;
Involvement of Sphingosineâ1âPhosphate/RhoA/RhoâKinase Signaling Pathway in Corporal Fibrosis Following Cavernous Nerve Injury in Male Rats
Keywords: گیرنده S1P; Penis; Fibrosis; Postprostatectomy Erectile Dysfunction; TGFâBeta; S1P Receptor; Sphingosine Kinase; RhoA; Rho Kinase;
Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus
Keywords: گیرنده S1P; sphingosine kinase; sphingosine 1-phosphate; S1P receptor; long-term potentiation; hippocampus; memory; ACSF; artificial cerebrospinal fluid; eEPSC; evoked excitatory postsynaptic current; fEPSP; field excitatory postsynaptic potentials; HACPT; 2-(p-hydro
Sphingosine kinase-1/S1P1 signalling axis negatively regulates mitogenic response elicited by PDGF in mouse myoblasts
Keywords: گیرنده S1P; S1P; sphingosine 1-phoshate; SK; sphingosine kinase; S1PR; S1P receptor; DMEM; Dulbecco's modified Eagle's medium; BSA; bovine serum albumin; FCS; fetal calf serum; siRNA; short interfering RNA; SDS; sodium dodecyl sulphate; PAGE; polyacrylamide gel elect
Sphingosine 1-phosphate chemical biology
Keywords: گیرنده S1P; Sphingosine 1-phosphate; S1P; Sphingosine kinase; SPHK; S1P receptor; FTY720; Fingolimod
Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system
Keywords: گیرنده S1P; Sphingosine-1-phosphate; Sphingosine kinase; S1P Receptor; Signaling; Endothelial cell; Smooth muscle; Cardiomyocyte; Migration; Angiogenesis; Cardiac remodeling
Identification of the orphan GPCR, P2Y10 receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor
Keywords: گیرنده S1P; P2Y10 receptor; Sphingosine-1-phosphate; Lysophosphatidic acid; S1P receptor; LPA receptor; Orphan GPCR
Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures
Keywords: گیرنده S1P; Integrative signalling; S1P receptor; PDGF receptor; PTX
Synthesis and SAR studies of a novel class of S1P1 receptor antagonists
Keywords: گیرنده S1P; Sphingosine-1-phosphate; S1P receptor; Antagonist; Structure–activity relationships
2,5-Disubstituted pyrrolidine carboxylates as potent, orally active sphingosine-1-phosphate (S1P) receptor agonists
Keywords: گیرنده S1P; Pyrrolidines; Oxadiazole; S1P receptor; Immunosuppressants
Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells
Keywords: گیرنده S1P; Sphingolipid; Sphingosine 1-phosphate; S1P receptor; S1P1; Embryonal development; Differentiation; Endoderm; F9 cells
The role of sphingosine-1-phosphate in smooth muscle contraction
Keywords: گیرنده S1P; ASM; airway smooth muscle; [Ca2+]i; intracellular calcium concentration; CNP; C-type natriuretic peptide; CHO; Chinese hamster ovary; DAG; diacylglycerol; dihydro-S1P; sphinganine-1-phosphate; eNOS; endothelial nitric oxide synthase; ER; endoplasmic retic