کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10817120 1058670 2005 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of sphingosine-1-phosphate in smooth muscle contraction
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
The role of sphingosine-1-phosphate in smooth muscle contraction
چکیده انگلیسی
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that is known to mediate diverse cellular responses including cell growth, survival, and migration. Most of these effects have been attributed to its binding to a specific subfamily of G protein-coupled receptors (GPCR), namely S1P1-5. Recent studies have suggested that S1P also plays a prominent role in the contraction of various types of smooth muscle. This review provides a brief overview of its role in this process and also highlights how S1P-dependent signaling serves as an important regulator of smooth muscle contraction.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cellular Signalling - Volume 17, Issue 3, March 2005, Pages 289-298
نویسندگان
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