دانلود مقالات ISI درباره S1Pr + ترجمه فارسی

نقش جذب آرسنیک در اختلال عملکرد بافت چربی و پیامدهای احتمالی آن در پاتوفیزیولوژی دیابت

Role of arsenic exposure in adipose tissue dysfunction and its possible implication in diabetes pathophysiology

Keywords: As(III); arsenite; As(V); arsenate; MMA; monomethylarsonic acid; Nox 2; NADPH oxidase; NOS; nitric oxide synthases; ETC; electron transport chain; WAT; white adipose tissue; BAT; brown adipose Tissue; UCP; uncoupling protein; α-KDGH; α-ketoglutarate deh

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

کنترل اسیدهای صفراوی متابولیسم و ​​التهاب در چاقی، دیابت نوع 2، دیس لیپیدمی و بیماری کبدی چربی غیرالکلی

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

Keywords: Bile Acids; FXR; TGR5; Meta-Inflammation; apo; apolipoprotein; ASBT; apical sodium−dependent bile acid transporter; BA; bile acid; BAS; bile acid sequestrant; BAT; brown adipose tissue; BSH; bile salt hydrolase; CA; cholic acid; CCK; cholecystokinin; CD

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

اسپینگسین-1-فسفات و استروژن سیگنالینگ در سرطان سینه

Sphingosine-1-phosphate and estrogen signaling in breast cancer

Keywords: Sphingosine-1-phosphate; Sphingosine kinase; Estradiol; Breast cancer; FTY720/Fingolimod; ERα; estrogen receptor α; EGFR; epidermal growth factor receptor; ERE; estrogen response element; ERK; extracellular signal regulated kinase; E2; 17β-estradiol; H

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

تجزیه و تحلیل نقش هدف سیگنالینگ رپامایسین در متابولیسم اسپینگولایپید

Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism

Keywords: AbA; Aureobasidin A; ABC; ATP-binding cassette; AMPK; AMP-activated protein kinase; ATG; Autophagy-related; ATP; Adenosine triphosphate; C1P; Ceramide-1-phosphate; CERS; Ceramide synthase; CK2; Casein kinase II; CLS; Chronological lifespan; CMA; Chaperone

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

اثرات اولیه دوز فینولیمود در بیماران مبتلا به مولتیپل اسکلروز عودکننده همزمان دریافت کننده مهارکننده های انتخابی بازدارنده سروتونین

Fingolimod first-dose effects in patients with relapsing multiple sclerosis concomitantly receiving selective serotonin-reuptake inhibitors

Keywords: AV; atrioventricular; AVB; atrioventricular block; ECG; electrocardiogram; FDA; US Food and Drug Administration; FDO; first-dose observation; FREEDOMS; FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis; GIRK; G-protein-gated i

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

آپولیپوپروتئین م

Apolipoprotein M

Keywords: apo; apolipoprotein; HDL; high-density lipoprotein; HNF-1α,4α; hepatocyte nuclear factor-1α,4α; LRH-1; liver receptor homolog-1; Foxa2; forkhead box A2; PAF; platelet activating factor; LXR; liver X receptor; RXR; retinoid X receptor; FXR; farnesoid X

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

فسفولیپید: یک روغن چرخ دار؟ از ایمنی هومورال

Phospholipids: “Greasing the wheels” of humoral immunity

Keywords: AP-1; activator protein-1; BLNK; B cell linker protein; BTK; Bruton's tyrosine kinase; CCT; choline cytidylyltransferase; CDP-choline; cytidine diphosphocholine; CEPT1; choline/ethanolamine phosphotransferase 1; Cer; ceramide; CK; choline kinase; CPT1; ch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia

Keywords: OGD; Oxygen glucose deprivation; S1P; Sphingosine-1-phosphate; S1Pr; Sphingosine-1-phosphate receptor; Sgpl1; Sphingosine-1-phosphate lyase; SPH; Sphingosine; SphK1; Sphingosine kinase 1; SphK2; Sphingosine Kinase 2; Spns2; Spinster 2; tGCI; Transient glo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling

Keywords: HCC; Hepatocellular carcinoma; GENT; gene expression across normal and tumor tissue; Acer3; Alkaline ceramidase 3; S1PR; Sphingosine-1-phosphate receptor; Hepatocellular carcinoma; Ceramidase; S1P; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Sphingosine-1-phosphate mediates the therapeutic effects of bone marrow mesenchymal stem cell-derived microvesicles on articular cartilage defect

Keywords: MVs; microvesicles; MSCs; mesenchymal stem cells; S1P; sphingosine-1-phosphate; S1PR; S1P receptor; IL-1β; interleukin 1 beta; GFP; green fluorescent protein; TEM; transmission electron microscopy; PBS; phosphate buffered saline; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis

Keywords: Nonalcoholic Fatty Liver Disease; Triglycerides; Fatty Acids; Therapy; AA; arachidonic acid; ACC; acetyl-coenzyme A carboxylase; ASMase; acid sphingomyelinase; CeS; ceramide synthase; CoA; coenzyme A; COX; cyclo-oxygenase; DES; dihydro-ceramide desatura

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1

Keywords: Angiotensin II; Vascular smooth muscle cell (VSMC); Sphingosine-1-phosphate receptor (S1PR); APE/Ref-1; Vascular neointima; DCF-DA; 6-carboxy-2′,7′-dichlorofluoroscein diacetate; Ang II; angiotensin II; AT; Ang II receptor; APE/Ref-1; apurinic/apyrimi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Pleiotropic FTY720 Is a Specific and Potent Therapy for Hypertrophic Scars

Keywords: α-SMA; α-smooth muscle actin; Akt; protein kinase B; FTY720; 2-amino-2-[2-(4-octylphenyl)]-1, 3-propanediol hydrochloride; HS; hypertrophic scarring; HSF; hypertrophic scar fibroblast; NF; normal fibroblast; S1P; sphingosine-1-phosphate; S1PR; sphingosi

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Dual signaling evoked by oxidized LDLs in vascular cells

Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts

Keywords: DMEM; Dulbecco's Modified Eagle Medium; FBS; fetal bovine serum; BSA; bovine serum albumin; PBS; phosphate buffered saline; DTT; dithiothreitol; INF-γ; interferon-γ; IGF1; insulin-like growth factor1; S1P; sphingosine 1-phosphate; SK1; sphingosine kinas

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Citron Rho-interacting kinase mediates arsenite-induced decrease in endothelial nitric oxide synthase activity by increasing phosphorylation at threonine 497: Mechanism underlying arsenite-induced vascular dysfunction

Keywords: EC; endothelial cells; ROS; reactive oxygen species; NO; nitric oxide; eNOS; endothelial NO synthase; PP1; protein phosphatase 1; AMPK; AMP-activated protein kinase; PKC; protein kinase C; PP2A; protein phosphatase 2A; CRIK; citron Rho-interacting kinase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Keywords: ABC; ATP-binding cassette transporter; AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase; AhR; arylhydrocarbon receptor; AKR1C1; aldo-keto reductase 1C1; APO; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BAs; bile acids; BSEP; b

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype

Keywords: Akt; PKB, protein kinase B; BDNF; brain derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CIDP; chronic inflammatory demyelinating polyneuropathy; CNS; central nervous system; Cx32; connexin-32; DMSO; dimethyl sulfoxide; DRG; dorsal root

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Corticotrophin-releasing factor participates in S1PR3-dependent cPLA2 expression and cell motility in vascular smooth muscle cells

Keywords: CRF receptors; cPLA2; Sphk1; S1PR; Cell motility;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Research reportFingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment

Keywords: oAβ; oligomeric amyloid β; BDNF; brain-derived neurotrophic factor; NORT; novel-object recognition test; S1P; sphingosine-1-phosphate; S1PR; sphingosine-1-phosphate receptor; Trk; tropomyosin-related kinase; Fingolimod; Alzheimer's disease; Amyloid β;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Role of Ca2+-dependent and Ca2+-sensitive mechanisms in sphingosine 1-phosphate-induced constriction of isolated porcine retinal arterioles in vitro

Keywords: sphingosine 1-phosphate; S1P; S1P receptor 2; porcine retinal arterioles; protein kinase C; vasoconstriction; RBF; retinal blood flow; S1P; sphingosine 1-phosphate; S1PR; S1P receptor; ROCK; rho-associated coiled-coil-forming protein kinase; PKC; protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Fingolimod in relapsing multiple sclerosis: An integrated analysis of safety findings

Keywords: AV; atrioventricular; FREEDOMS; FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis; HPS; haemophagocytic syndrome; LRTI; lower respiratory tract infection; MS; multiple sclerosis; PML; progressive multifocal leukoencephalopathy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleSphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis

Keywords: S1P; sphingosine-1-phosphate; SphK; sphingosine kinase; S1PR; S1P receptor; VEGF; vascular endothelial growth factor; HSC; hepatic stellate cells; Ang1; angiopoietin 1; SKI; 2-(p-hydroxyanilino)-4-(p-chloro-phenyl)thiazole; BDL; bile duct ligation; HPLC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological targets in the renal peritubular microenvironment: Implications for therapy for sepsis-induced acute kidney injury

Keywords: AKI; acute kidney injury; RBF; renal blood flow; MAP; mean arterial pressure; GFR; glomerular filtration rate; LPS; lipopolysaccharide; CLP; cecal ligation and puncture; MMP; matrix metalloproteinase; S1P; sphingosine-1-phosphate; S1PR; sphingosine-1-phos

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Sphingosine-1-phosphate acting via the S1P1 receptor is a downstream signaling pathway in ceramide-induced hyperalgesia

Keywords: SphK; sphingosine kinase; S1P; shingosine-1-phosphate; S1PR1; shingosine-1-phosphate receptor subtype 1; S1PR; G-protein coupled S1P receptors; SK-I; 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole; Ceramide; Sphingosine-1-phosphate; Sphingosine kinase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Sphingosine kinase-1/S1P1 signalling axis negatively regulates mitogenic response elicited by PDGF in mouse myoblasts

Keywords: S1P; sphingosine 1-phoshate; SK; sphingosine kinase; S1PR; S1P receptor; DMEM; Dulbecco's modified Eagle's medium; BSA; bovine serum albumin; FCS; fetal calf serum; siRNA; short interfering RNA; SDS; sodium dodecyl sulphate; PAGE; polyacrylamide gel elect

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

The role of sphingosine-1-phosphate in smooth muscle contraction

Keywords: ASM; airway smooth muscle; [Ca2+]i; intracellular calcium concentration; CNP; C-type natriuretic peptide; CHO; Chinese hamster ovary; DAG; diacylglycerol; dihydro-S1P; sphinganine-1-phosphate; eNOS; endothelial nitric oxide synthase; ER; endoplasmic retic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه