Keywords: AA; arachidonic acid; AM; acetoxymethyl; CalDAG-GEFI; calcium- and DAG-regulated guanine nucleotide exchange factor 1; COX; cyclooxygenase; DAG; diacylglycerol; FITC; fluorescein isothiocyanate; FSC; forward scatter; GS; stimulatory G-protein; IP3; inosit
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Keywords: Sitagliptin; BNP; cGMP; PKG; Cyp D;
Keywords: TCM; Traditional Chinese medicine; YXST; Yangxinshi tablet; SPR; Surface plasmon resonance; PPARγ; Peroxisome proliferator-activated receptor gamma; ACE; Angiotensin-converting enzyme; MAPK; Mitogen-activated protein kinase 14; KEGG; Kyoto Encyclopedia o
Keywords: Top-down mass spectrometry; Sarcomeres; Post-translational modification; Phosphorylation; AP; alkaline phosphatase; cAMP; cyclic adenosine monophosphate; CK2; casein kinase 2; ECD; electron capture dissociation; ELC; essential light chain; ELISA; enzyme-l
Keywords: AAD; allergic airways disease; AECs; amnion epithelial cells; AHF; acute heat failure; AHR; airway hyperresponsiveness; Ang II; angiotensin II; AT2; angiotensin type 2 receptor; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; ERK; extrac
Keywords: ATP; adenosine triphosphate; CBX; carbenoxolone; C-terminus; carboxyl-terminus; CNS; central nervous system; EL; extracellular loop; Gly0; core glycosylation; Gly1; high mannose glycosylation; Gly2; complex glycosylation; ICL; intracellular loop; N2a; Neu
Keywords: AMA-1; apical membrane antigen 1; 2 -APB; 2-aminoethoxydiphenyl borate; BMP; bis (monoacylglycerol)phosphate; CDP; cytidine diphosphate-choline; cGMP; cyclic guanosine monophosphate; D; aspartate; DAG; diacylglycerol; EBA175; erythrocyte binding antigen 1
Keywords: AC; adenylate cyclase; ADHD; attention deficit hyperactivity disorder; ACC; anterior cingulate cortex; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATP; adenosine triphosphate; BBB; blood-brain barrier;
Keywords: AGE; Advanced Glycation End products; ALDH2; aldehyde dehydrogenase 2; AngII; angiotensin II; BKCa; large conductance Ca2+-activated K+ channel; Ca2+; calcium; [Ca2+]c; cytosolic free Ca2+ concentration; CaD; caldesmon, CaM, calmodulin; cAMP; cyclic adeno
Keywords: AMPK; AMP-activated protein kinase; cGMP; cyclic guanosine monophosphate; EDH; endothelium-dependent hyperpolarization; H2O2; hydrogen peroxide; NO; nitric oxide; NOS; nitric oxide synthase; PGs; prostaglandins; PKG; cGMP-dependent protein kinase; ROS; re
Keywords: Kappa opioid receptor; Serotonin; Clearance; Serotonin transporter; Phosphorylation; Trafficking; 5-HT; 5-hydroxytryptamine (serotonin); Akt X; Akt inhibitor X (10-(4â²-(N-diethylamino)butyl)-2-chlorophenoxazine); Akt; protein kinase B/Akt; BNI; nor-bina
Keywords: AS; Angeli's salt; AST; aspartate aminotransferase; ALT; alanine transaminase; BALF; bronchoalveolar lavage fluid; CGRP; calcitonin gene-related peptide; COX-2; cyclooxygenase-2; CFU; colony-forming unity; cGMP; cyclic guanosine monophosphate; PKG; cGMP-d
Keywords: [Ca++]i; intracellular Ca2+ concentration; 2ME2; 2-methoxyestradiol, a natural metabolite of estradiol; 4-OH-Tmx; 4-hydroxytamoxifen, a metabolite of Tmx; 5-HT3R; 5-hydroxytryptamine receptor subtype 3; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropio
Keywords: BKCa channels; PKG; Prenatal HS; Renal interlobar arteries; sGC
Keywords: ANP; atrial natriuretic peptide; BKCa; large-conductance Ca2Â + activated potassium channels; cAMP; cyclic adenosine 3,5â²-monophosphate; CNG; cyclic nucleotide-gated; cGMP; cyclic guanosine 3,5â²-monophosphate; HUASMC; human umbilical artery smooth mus
Keywords: 5-HIAA; 5-hydroxyindoleacetic acid; ASD; autism spectrum disorder; ITGB3; integrin β3 subunit gene; MAOA; mitochondrial bound protein monoamine oxidase A; MAPK; mitogen-activated protein kinase; MDMA; 3,4-methylenedioxymethamphetamine; NAS; N-acetylserot
Keywords: ANT; adenine nucleotide translocase; CsA; cyclosporin A; CyP; cyclophilin; Drp1; dynamin-related protein 1; ÎÏm; mitochondrial membrane potential; ERK; extracellular signal regulated kinase; GSK; glycogen synthase kinase; IMM; inner mitochondrial membra
Keywords: lHCC; hepatocellular carcinoma; ECM; extracellular matrix; FBLP-1; filamin binding LIM protein -1 (or Migfilin); VASP; vasodilator stimulated phosphoprotein; PBGD; porphobilinogen deaminase; PKA; cAMP-dependent kinase; PKG; cGMP-dependent protein kinase;
Keywords: GSNO; S-nitrosoglutathione; MNTB; medial nucleus of the trapezoid body; NOC-5; 3-(aminopropyl)-1-hydroxy-3-isopropyl-2-oxo-1-triazene; PAPA NONOate; 3-(2-hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine; PKG; protein kinase G; SNAP; S-nitroso-N-acetylpe
Keywords: cNMPs; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases; Bacterial toxins; Second messengers; AC; adenylyl cyclase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CC; cytidylyl cyclase; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanos
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; cTMP; thymidine 3
Keywords: AKAPs; A-kinase anchoring proteins; AKT; protein kinase b; Ang-II; angiotensin II; ASK1; apoptosis signal-regulating kinase 1; BH4; tetrahydrobiopterin; CaMKII; Ca/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CHF; chronic heart fa
Keywords: AKT; protein kinase B; CAV-3; caveolin-3; Cyt c; cytochrome c; eNOS; endothelial nitric oxide synthase; ERK1/2; extracellular signal-regulated kinase 1/2; GRK2; G-protein coupled receptor kinase 2; GSK3β; glycogen synthase kinase 3β; MEK; MAPK/ERK kinas
Keywords: AC; adenylyl cyclase; ALDH; aldehyde dehydrogenase; ANT; adenine nucleotide transporter; AR; adrenergic receptor; ARE; antioxidant response element; ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; COX; cyclo-oxygenase; CsA; cyclosporine
Keywords: Ï-CTX; Ï-conotoxin GVIA; BIM; BIM 23056; CYN; CYN-154806; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EGTA; ethylene glycol-bis(β-aminoethyl ether) N,N,Nâ²,Nâ²-tetraacetic acid; GABA; γ-aminobutyric acid; HEPES; 4-(2-hydr
Keywords: Cav3; caveolin-3; Cav3+LR; caveolin-3 enriched lipid raft, caveolae; cGMP; cyclic guanosine monophosphate; DEA/NO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate, diethylamine NONOate; ERK5; extracellular signal regulated kinase 5; LR; l
Keywords: BDNF; brain derived neurotrophic factor; CAMKII; calmodulin-dependent protein kinase II; Ca2+; calcium; cAMP; cyclic adenosine monophosphate; CBS; cystathionine-β-synthase; CCI; chronic constriction injury; CFA; complete Freund's adjuvant; cGMP; cyclic
The role of PKG in oocyte maturation of zebrafish
Keywords: Ovary; Oocyte maturation; Meiosis; PKG; cGMP; Zebrafish;
β3-adrenergic receptor activation induces TGFβ1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway
Keywords: β3-adrenergic receptor; Transforming growth factor β1; Protein kinase G; c-Jun N-Terminal kinase; c-Jun; Cardiomyocyte; AP-1; activator protein 1; β-AR; β-adrenergic receptor; cGMP; cyclic guanosine monophosphate; GRK; G protein-coupled receptor kinas
ERK1/2 inhibition increases dopamine release from differentiated PC12 cells
Keywords: PC12 cells; Dopamine; ERK1/2; U0126; PKG; PKA; Synapsin I; SNAP-25;
Rho kinase, a potential target in the treatment of metabolic syndrome
Keywords: WHO; World Health Organization; NCEP-ATP III; the National Cholesterol Education Program Adult Treatment Panel III; IDF; the International Diabetes Federation; JIS; the Joint Interim Societies; NCEP; National Cholesterol Education Program; MetS; metabolic
Expression and localization of phosphodiesterase 2A in the submandibular gland of mice
Keywords: cAMP; cyclic AMP; cGMP; cyclic GMP; PDE2A; phosphodiesterase 2A; NGF; nerve growth factor; PKA; protein kinase A; PKG; protein kinase G; PKG1; protein kinase G1; RT; PCR, reverse transcription-polymerase chain reaction; Serpinb6a; serine (or cysteine) pep
Low-concentration BPF induced cell biological responses by the ERα and GPER1-mediated signaling pathways in MCF-7 breast cancer cells
Keywords: ERα/β; (estrogen receptor alpha/beta); GPER1; (G-protein-coupled receptor 1); PI3K/PKB; (phosphatidylinotidol 3-kinase/Protein kinase B); ERK1/2; extracellular-signa1-regulated kinase; ICI; ICI182780; WM; wortmannin; MKH; MK-2206 2HCl; U; U0126; DCFH-DA
Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists
Keywords: 4-AP; 4-amynopiridine; AC; adenylyl cyclase; BPH; benign prostatic hyperplasia; COX; cyclooxygenase; DAG; diacylglycerol; EDHF; endothelium-derived hyperpolarizing factor; eNOS; endothelial NO synthase; GLI; glibenclamide; HAEC; human aortic endothelial c
HFpEF, a Disease of the Vasculature: A Closer Look at the Other Half
Keywords: cAMP; cyclic adenosine 3â²,5â²-monophosphate; cGMP; cyclic guanosine monophosphate; EF; ejection fraction; HFpEF; heart failure with preserved ejection fraction; HFrEF; heart failure with reduced ejection fraction; KO; knockout; LV; left ventricular; LZ
The anti-diabetic drug dapagliflozin induces vasodilation via activation of PKG and Kv channels
Keywords: Dapagliflozin; Aortic smooth muscle; Voltage-dependent K+ channel; PKG; Vasorelaxation;
A conjugate of decyltriphenylphosphonium with plastoquinone can carry cyclic adenosine monophosphate, but not cyclic guanosine monophosphate, across artificial and natural membranes
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; 8-Br-cAMP; 8-bromoadenosine 3â²,5â²-cyclic monophosphate; 8-Br-cGMP; 8-bromoguanosine 3â²,5â²-cyclic monophosphate; PKA; protein kinase A; PKG; protein kin
Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes
Keywords: dTg; double transgenic; ELISA; enzyme-linked immunosorbent assay; Fasn; fatty acid synthase; Gn; guanylin; GC-C; guanylyl cyclase C; HFD; high-fat diet; IL-2; interleukin-2; IL-2R; interleukin-2 receptor; IL-15; interleukin-15; IL-15R; interleukin-15 rece
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets
Keywords: Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple
Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1
Keywords: Thermogenesis; UCP1; Kinases; βAR; β-adrenergic receptor; 8-Br-cAMP; 8-Bromoadenosine 3â²,5â²-cyclic monophosphate; 8-Br-cGMP; 8-Bromoguanosine 3â²,5â²-cyclic monophosphate; Akt; protein kinase B; ANP; Atrial natriuretic peptide; BNP; B-type natriur
Extra-endothelial TRPV1 channels participate in alcohol and caffeine actions on cerebral artery diameter
Keywords: Ethanol; Caffeine; TRPV1 channel; Arterial smooth muscle; Cerebral artery; TRPV1 knockout mouse; BAL; blood alcohol level; BK; voltage-/calcium-gated potassium (channel) of large conductance; KO; knockout; MCA; middle cerebral artery; NOS; nitric oxide sy
AGC kinases, mechanisms of regulation âand innovative drug development
Keywords: AGC kinase; group of kinases related to PKA PKG and PKC; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PRK; protein kinase C related kinase (also termed PKN protein kinase N); PDK1; 3-phosphoinositide-dependent protein kinase 1; PKB
Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina
Keywords: Orexin; Retinal rod bipolar cell; GABA receptor; Neuromodulation; BCs; bipolar cells; BIC; bicuculline; Bis-IV; bisindolylmaleimide IV; CPPG; (RS)-α-cyclopropyl-4-phosphor- nophenylalycine; DAG; diacylglycerol; DLG; dorsal lateral geniculate nucleus; DT-
Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension
Keywords: ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB
Clinical benefits and pharmacology of scutellarin: A comprehensive review
Keywords: Aβ; β-amyloid peptide; ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; ADE; adverse drug effect; ADR; adverse drug reaction; AIF; apoptosis-inducing factor; Akt; protein kinase B or PKB; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activat
GSK-3 mediates NO-cGMP-induced isoflavone production in soybean sprouts
Keywords: cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; NO; nitric oxide; SNP; sodium nitroprusside; LY-83583; 6-Anilino-5,8-quinolinequinone; GC; guanylyl cyclase; cGMP; guanosine 3â²,5â²-cyclic monophosphate; PKG; protein kinase G; G
Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells
Keywords: HASMC; human arterial smooth muscle cell; cAMP; 3â²5â², cyclic adenosine monophosphate; cGMP; 3â²5â², cyclic guanosine monophosphate; PDE; cyclic nucleotide phosphodiesterase; PKA; protein kinase A; PKG; protein kinase G; IP3; inositol-1, 4, 5-trispho
Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells
Keywords: CBS; cystathionine β-synthase; CSE; cystathionine γ-lyase; Drp1; dynamin-related protein 1; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; ERK; extracellular signal-regulated kinase; G protein; GTP-binding protein; GC; guanylate cyclase; GDP; guanosine 5'
Regulation of L-type CaV1.3 channel activity and insulin secretion by the cGMP-PKG signaling pathway
Keywords: L-type channels; Cav channels; PKG; cGMP; Insulin; Rin-m5F cells;
Research paperSpecific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent β3-adrenergic signaling
Keywords: VR; visible radiation; Opn1; cone opsin; Opn2; type II opsin; β2-AR; beta-2 adrenergic receptor; β3-AR; beta-3 adrenergic receptor type 3; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; cGMP; cyclic guanosine monophosphate; PKG; protein ki