ORIGINAL RESEARCH-BASIC SCIENCE: The PDE5 Inhibitor Sildenafil Increases Circulating Endothelial Progenitor Cells and CXCR4 Expression

These data allow us to suppose an involvement of PDE5 in bone marrow release and peripheral homing of EPC. Foresta C, De Toni L, Di Mambro A, Garolla A, Ferlin A, and Zuccarello D. The PDE5 inhibitor sildenafil increases circulating endothelial progenitor cells and CXCR4 expression. J Sex Med 2009;6:369-372.