کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4279421 | 1611526 | 2012 | 8 صفحه PDF | دانلود رایگان |
BackgroundWhen patients with drug-eluting stents (DES) present for surgery, current guidelines recommend delaying elective surgeries until 1 year of dual antiplatelet therapy has been completed.MethodsWe performed a systematic literature review of the major adverse cardiac events (MACE) associated with noncardiac surgery in patients with DES.ResultsTwenty-eight of 358 studies met inclusion criteria. Overall, MACE rates decreased as time to surgery increased and varied from 0% to 18% for surgeries within 1 year as compared with 0% to 12% for surgery more than 1 year after a stent. In addition, the current literature showed limited evidence for a protective effect of continuing perioperative dual antiplatelet therapy on MACE rates.ConclusionsThe current literature supports a significant decrease in MACE when surgery is performed 1 year after DES placement; however, the level of evidence is weak. Larger studies are needed to determine the safe interval for surgery after stent placement.
Journal: The American Journal of Surgery - Volume 204, Issue 4, October 2012, Pages 494–501