کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
431058 1441279 2008 39 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pathway analysis for BioAmbients
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر نظریه محاسباتی و ریاضیات
پیش نمایش صفحه اول مقاله
Pathway analysis for BioAmbients
چکیده انگلیسی

Systems Biology aims for a holistic understanding of biological processes. In order to make this understanding operational and testable it can be recorded into formal process calculus models. This is a difficult task, however, because such formal models and their, often infinitely many, consequences are hard to enumerate and understand. In this paper we define a pathway analysis, based on static analysis techniques from programming languages, and show how it can be used to establish useful, finite, approximations to the set of causal consequences of models. The Pathway Analysis can be used to great advantage in all phases of the modelling approach – serving as the basis of debugging during model development, postdiction during model validation, and, finally, prediction during model guided drug design.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Logic and Algebraic Programming - Volume 77, Issues 1–2, September–October 2008, Pages 92-130