کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4343699 | 1615122 | 2014 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Decline of umami preference in aged rats
ترجمه فارسی عنوان
کاهش ترجیح اومامی در موش های سالم
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کلمات کلیدی
سالخورده، ترجیح طعم، طعم پاسخ های عصب امامی، شیرین،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
The effects of aging on the umami sensation were compared between the preference and neural responses from the greater superficial petrosal nerve (GSP innervating the soft palate) and the chorda tympani nerve (CT innervating the fungiform papillae) in the Sprague Dawley rat. A two-bottle preference test revealed that younger rats (5-12 weeks) preferred significantly 0.001Â M 5â²-inosine monophosphate (IMP), 0.01Â M mono sodium glutamate (MSG), and binary mixtures of 0.001Â M IMPÂ +Â 0.01Â M MSG than deionized water. However, aged rats (21-22 months) showed no significant preference to these umami solutions compared to deionized water. Among the other four basic taste stimuli, there were no significant differences in preference between young and aged rats. Regardless of the age of the rat, neural responses from the GSP and CT produced robust integrated responses to all three umami solutions used in the two-bottle tests. These results indicate that the lack of preference to umami in aged rats is a central nervous system phenomenon and suggests that the loss of preference to umami taste in aged rats is caused by homeostatic changes in the brain incurred by aging.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 577, 8 August 2014, Pages 56-60
Journal: Neuroscience Letters - Volume 577, 8 August 2014, Pages 56-60
نویسندگان
Hirohito Miura, Makoto Ooki, Norikazu Kanemaru, Shuitsu Harada,