Effects of optimized-SopungSunkiwon on memory impairment and enhancement

▶ Optimized-SopungSunkiwon (OSS), a multi-herbal formula, inhibited AchE activity. ▶ OSS-treatment elevate the latency time longer than scopolamine-treated mice in the passive-avoidance test. ▶ OSS-treatment significantly increased synaptophysin and PSD-95. ▶ OSS affects memory impairment and enhancement by inducing synaptic proteins.