کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4406394 1618678 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prediction and characterization of microRNAs from eleven fish species by computational methods
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بوم شناسی
پیش نمایش صفحه اول مقاله
Prediction and characterization of microRNAs from eleven fish species by computational methods
چکیده انگلیسی

MicroRNAs (miRNAs) are a family of single-stranded RNA molecules about 22 nt in length, which can regulate protein-coding gene expression in various organisms by post-transcriptional repression of messenger. In this research, the potential miRNAs and their target genes were analyzed and predicted by computational methods from the EST and GSS databases of eleven fish species, 43 potential miRNAs were identified, they belong to 38 miRNA families, some miRNAs are highly conserved in animal kingdom, the predicted target genes are involved in development, signal transduction, response to environmental stress and pathogen invasion. Taken together, our data suggest that there are a plentiful of miRNAs in these eleven fish species, these miRNAs may play some important roles by regulating their target genes, and the data provide important information for further functional studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Saudi Journal of Biological Sciences - Volume 22, Issue 4, July 2015, Pages 374–381
نویسندگان
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