کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4412649 1307647 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patterns and concentration levels of polybrominated diphenyl ethers (PBDEs) in placental tissue of women in Denmark
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Patterns and concentration levels of polybrominated diphenyl ethers (PBDEs) in placental tissue of women in Denmark
چکیده انگلیسی

The levels and congener patterns of PBDEs were investigated in human placental samples in Denmark. The median concentrations of ∑PBDEtri-hepta and BDE-209 in the 50 samples were 1.22 and 1.14 ng g−1 lw, respectively, with the total sum ranging from 0.51 to 17.1 ng g−1 lw, which is similar to previous placental studies. The PBDE content in placental tissue was dominated by BDE-209, which accounted for approximately 50% of the total amount of PBDEs. BDE-47, -99, and -153 were detected in all samples. Approximately equal amounts of BDE-47 and BDE-153 were observed in the placental tissue, which is in agreement with previous European studies of human serum. Principal Component Analysis (PCA) was performed to analyze congener patterns within and between mothers. The loading plot showed groupings of the measured PBDE variables in three groups, representative of Penta-, Octa- and Deca-BDE technical mixtures. Congeners representing the individual technical mixtures were close to orthogonal or inversely correlated, indicating variation in the congener patterns of internal exposure corresponding to the patterns of technical mixtures used in products. Visualisation of the participant objects according to body mass index (BMI), revealed inherent congener patterns (19% X-variance) showing increased frequency for participants within the highest BMI group to have elevated concentrations of BDE-209 in the placental tissue.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 76, Issue 11, September 2009, Pages 1464–1469
نویسندگان
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