کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4413147 1307666 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dioxins in adipose tissue of women in Southern Spain
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Dioxins in adipose tissue of women in Southern Spain
چکیده انگلیسی

Seventeen polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) were quantified in adipose tissue samples of non-occupationally exposed women living in Southern Spain. Geometric mean levels of sum of congeners and WHOPCDD/F-TEQ2005 were 410 and 17.9 pg g−1 fat, respectively. Among PCDDs, octachlorodibenzo-p-dioxin (OCDD) showed the highest concentration with a mean value of 265 pg g−1 fat, followed by 1,2,3,6,7,8-HxCDD (49.3 pg g−1 fat) and 1,2,3,4,6,7,8-HpCDD (45.2 pg g−1 fat). These three congeners were responsible for around 90% of the sum of all PCDD/F congeners in adipose tissue. The geometric mean 2,3,7,8-TCDD value was 1.87 pg g−1 fat. 2,3,4,7,8-PeCDF (8.43 pg g−1 fat) showed the highest concentration among the PCDFs, followed by 1,2,3,4,7,8-HxCDF (4.17 pg g−1 fat) and 1,2,3,6,7,8-HxCDF (3.28 pg g−1 fat), and these three congeners were responsible for 4% of the sum of all studied PCDD/F congeners in adipose tissue and 76% of the sum of ten PCDFs. 1,2,3,7,8,9-HxCDF was the only congener not quantified in any sample, while 1,2,3,4,7,8,9-HpCDF, 1,2,3,7,8-PeCDF, OCDF and 2,3,7,8-TCDF were found in 5, 16, 16 and 19 samples, respectively. All other congeners were quantifiable in all 20 samples. Congeners contributing most to the WHOPCDD/F-TEQ2005 were 1,2,3,7,8-PeCDD (31.6%), 1,2,3,6,7,8-HxCDD (28.3%) and 2,3,4,7,8-PeCDF (14.6%). The body burden of log-transformed WHOPCDD/F-TEQ2005 levels increased with age (B = 0.02; 95% CI = 0.01, 0.03; p = 0.02). Although these adipose tissue PCDD/F levels are similar to previously published findings in Spain and other European countries, further research is needed to determine trends in the exposure of women to these chemical residues.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 73, Issue 6, October 2008, Pages 967–971
نویسندگان
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