Global contamination of coplanar polybrominated/chlorinated biphenyls (Co-PXBs) in the market fishes from Japan

Polybrominated chlorinated biphenyls (PXBs, X = Br, Cl) are a group of environmental contaminants that have not been studied previously. The introduction of the second halogen to the biphenyl backbone increases the number of possible congeners to more than 9000. Only a limited number of PXBs are commercially available. In order to determine the occurrence of these compounds in environmental matrices, an isotope dilution HRGC/HRMS method for determination of five co-planar polybrominated/chlorinated biphenyls (Co-PXBs) in biota was developed. The method detection limit for these compounds ranged between 0.05 and 0.5 pg/g for 4′4′-monobromo-3,3′3′,4,5-tetrachlorobiphenyl and 3′3′,4′4′,5′5′-tribromo-3,4-dichlorobiphenyl, respectively.Concentrations of five co-planar polybrominated and chlorinated biphenyls in eighteen different fish fillets from Japanese markets ranged between 4 and 46 pg/g wet weight for mink whale and young yellow-tail fish. These values are substantially lower than those reported for Co-PCBs; however, it should be noted that due to the unavailability of standards, identification and quantification of all the isomers was not possible.