کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4502597 1320583 2010 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The fixation probability of two competing beneficial mutations
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
The fixation probability of two competing beneficial mutations
چکیده انگلیسی
Suppose that a beneficial mutation is undergoing a selective sweep when another beneficial mutation arises at a linked locus. We study the fixation probability of the double mutant, i.e., one (produced by recombination) that carries both mutations. Previous analysis works well for the case where the earlier beneficial mutation confers a greater selective advantage than the later mutation, but not so well in the opposite case. We present an approach to approximating the fixation probability in the case where the later mutation confers a greater selective advantage.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theoretical Population Biology - Volume 78, Issue 1, August 2010, Pages 36-45
نویسندگان
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