کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4502803 1320601 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mean curvature versus normality: A comparison of two approximations of Fisher's geometrical model
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Mean curvature versus normality: A comparison of two approximations of Fisher's geometrical model
چکیده انگلیسی

Fisher's geometrical model amounts to a description of mutation and selection for individuals characterised by a number of quantitative traits. In the present work the fitness landscape is not assumed to be spherically symmetric, hence different points, i.e. phenotypes, on a surface of constant fitness generally have different curvatures. We investigate two different approximations of Fisher's geometrical model that have appeared in the literature. One approximation uses the average curvature of the fitness surface at the parental phenotype. The other approach is based on a normal approximation of a distribution associated with new mutations. Analytical results and simulations are used to compare the accuracy of the two approximations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theoretical Population Biology - Volume 71, Issue 1, February 2007, Pages 30–36
نویسندگان
,