کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4677 237 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microbial enantioselective reduction of ethyl-2-oxo-4-phenyl-butanoate
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Microbial enantioselective reduction of ethyl-2-oxo-4-phenyl-butanoate
چکیده انگلیسی

Different microorganisms (MOs) were used to carry out the enantioselective reduction of ethyl-2-oxo-4-phenylbutanoate to (S)-(+)-2-hydroxy-4-phenylbutanoate or (R)-(+)-2-hydroxy-4-phenylbutanoate. Commercially available Saccharomyces cerevisiae and Dekera sp. led to over 92% ee of (S)-(+)-2-hydroxy-4-phenylbutanoate. Kluyveromyces marxianus gave the opposite isomer with 32% ee (R). All reactions, except those with Hansenula sp., proceeded to greater than 90% conversion. This the first report on the use of Dekera sp., Hansenula sp. and K. marxianus in the reduction of α-ketoesters.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical Engineering Journal - Volume 28, Issue 3, 1 March 2006, Pages 299–302
نویسندگان
, , , , , ,