کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
469599 698334 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extremal Optimization for protein folding simulations on the lattice
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
Extremal Optimization for protein folding simulations on the lattice
چکیده انگلیسی

This paper presents a novel guided search strategy Extremal Optimization (EO) with constrained structure for protein folding. In the proposed algorithm, evaluating the fitness of each monomer in an amino-acid sequence is introduced to guide the improvement of the conformation. In addition, a constrained structure is proposed to reduce the complexity of algorithm. We demonstrate that EO can be applied successfully to the protein folding problem. The results show that the algorithm can find the best solutions so far for the listed benchmarks. Within the achieved results, the search converged rapidly and efficiently.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers & Mathematics with Applications - Volume 57, Issues 11–12, June 2009, Pages 1855–1861
نویسندگان
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