کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
471187 698603 2008 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lagrangian approaches for a class of matching problems in computational biology
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
Lagrangian approaches for a class of matching problems in computational biology
چکیده انگلیسی

This paper presents efficient algorithms for solving the problem of aligning a protein structure template to a query amino-acid sequence, known as protein threading problem. We consider the problem as a special case of graph matching problem. We give formal graph and integer programming models of the problem. After studying the properties of these models, we propose two kinds of Lagrangian relaxation for solving them. We present experimental results on real-life instances showing the efficiency of our approaches.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers & Mathematics with Applications - Volume 55, Issue 5, March 2008, Pages 1054–1067
نویسندگان
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