کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5031121 | 1470941 | 2017 | 53 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions
ترجمه فارسی عنوان
رویکردهای میکروارگانیسم برای جداسازی، تشخیص و شناسایی حاملهای خارج سلولی: وضعیت فعلی و جهت آینده
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an essential role in various cellular processes, such as intercellular communication, inflammation, cellular homeostasis, survival, transport, and regeneration. Their isolation and analysis from body fluids have a great clinical potential to provide information on a variety of disease states such as cancer, cardiovascular complications and inflammatory disorders. Despite increasing scientific and clinical interest in this field, there are still no standardized procedures available for the purification, detection, and characterization of EVs. Advances in microfluidics allow for chemical sampling with increasingly high spatial resolution and under precise manipulation down to single molecule level. In this review, our objective is to give a brief overview on the working principle and examples of the isolation and detection methods with the potential to be used for extracellular vesicles. This review will also highlight the integrated on-chip systems for isolation and characterization of EVs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 91, 15 May 2017, Pages 588-605
Journal: Biosensors and Bioelectronics - Volume 91, 15 May 2017, Pages 588-605
نویسندگان
Shima Gholizadeh, Mohamed Shehata Draz, Maryam Zarghooni, Amir Sanati-Nezhad, Saeid Ghavami, Hadi Shafiee, Mohsen Akbari,