کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5032772 | 1369996 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Rôle of contrast media viscosity in altering vessel wall shear stress and relation to the risk of contrast extravasations
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Rôle of contrast media viscosity in altering vessel wall shear stress and relation to the risk of contrast extravasations Rôle of contrast media viscosity in altering vessel wall shear stress and relation to the risk of contrast extravasations](/preview/png/5032772.png)
چکیده انگلیسی
Iodinated contrast media (CM) are the most commonly used injectables in radiology today. A range of different media are commercially available, combining various physical and chemical characteristics (ionic state, osmolality, viscosity) and thus exhibiting distinct in vivo behaviour and safety profiles. In this paper, numerical simulations of blood flow with contrast media were conducted to investigate the effects of contrast viscosity on generated vessel wall shear stress and vessel wall pressure to elucidate any possible relation to extravasations. Five different types of contrast for Iodine fluxes ranging at 1.5-2.2Â gI/s were modelled through 18Â G and 20Â G cannulae placed in an ideal vein at two different orientation angles. Results demonstrate that the least viscous contrast media generate the least maximum wall shear stress as well as the lowest total pressure for the same flow rate. This supports the empirical clinical observations and hypothesis that more viscous contrast media are responsible for a higher percentage of contrast extravasations. In addition, results support the clinical hypothesis that a catheter tip directed obliquely to the vein wall always produces the highest maximum wall shear stress and total pressure due to impingement of the contrast jet on the vessel wall.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Engineering & Physics - Volume 38, Issue 12, December 2016, Pages 1426-1433
Journal: Medical Engineering & Physics - Volume 38, Issue 12, December 2016, Pages 1426-1433
نویسندگان
Sophia Sakellariou, Li Wenguang, Manosh C Paul, Giles Roditi,