Gold nanorods reflectance discriminate benign from malignant oral lesions

Tissue sections of oral squamous cell carcinoma incubated with gold nanorods bio-conjugated to anti-epidermal growth factor receptor monoclonal antibodies and the reflectance spectrum measured using hyperspectral microscopy. Tissue sample is Halogen illuminated and the reflected light detected from its surface. The hyperspectral camera enables spectrum analyses of each pixel on the tissue picture.114