کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5124126 1488124 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Insights Into the Role of Collagen in Vocal Fold Health and Disease
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
Insights Into the Role of Collagen in Vocal Fold Health and Disease
چکیده انگلیسی

SummaryAs one of the key fibrous proteins in the extracellular matrix, collagen plays a significant role in the structural and biomechanical characteristics of the vocal fold. Anchored fibrils of collagen create secure structural regions within the vocal folds and are strong enough to sustain vibratory impact and stretch during phonation. This contributes tensile strength, density, and organization to the vocal folds and influences health and pathogenesis. This review offers a comprehensive summary for a current understanding of collagen within normal vocal fold tissues throughout the life span as well as vocal pathology and wound repair. Further, collagen's molecular structure and biosynthesis are discussed. Finally, collagen alterations in tissue injury and repair and the incorporation of collagen-based biomaterials as a method of treating voice disorders are reviewed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Voice - Volume 31, Issue 5, September 2017, Pages 520-527
نویسندگان
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