کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5130716 | 1490847 | 2017 | 10 صفحه PDF | دانلود رایگان |
- A novel stir-bead micro-solid phase extractor was developed.
- Large interconnected pore of chitosan cryogel incorporated with polypyrrole as adsorbent was prepared.
- A polypyrrole-chitosan cryogel stir-bead was applied for the preconcentration and extraction of trace phthalate esters.
Phthalate esters (PAEs), especially dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), di-2-ethylhexyl phthalate (DEHP) are widely used as plasticizers in plastics and polymers. They are not chemically bound and can easily migrate into food and human tissue that comes into contact with these materials. The method developed in this work was applied for the preconcentration and determination of these four phthalate esters that might leach from contact lenses and baby teethers. A novel stir-bead micro-solid phase extractor of chitosan cryogel composited with polypyrrole with a steel wire core was evaluated for the extraction of DMP, DEP, DBP and DEHP before analysis by high performance liquid chromatography (HPLC). Scanning electron micrographs of the polypyrrole-chitosan cryogel beads revealed a high porosity with large surface area. Under the optimum conditions, the developed method provided a good linearity in a concentration range from 10 to 750 ng mLâ1 for DMP and from 5.0 to 750 ng mLâ1 for DEP, DBP and DEHP. The limits of detection (LOD) were 6.07 ± 0.22 ng mLâ1, 4.358 ± 0.097 ng mLâ1, 4.408 ± 0.099 ng mLâ1 and 3.916 ± 0.053 ng mLâ1 for DMP, DEP, DBP and DEHP, respectively, and the method reproducibility was good (n = 6, % RSD < 6.0). DBP and DEHP were detected in two original storage solutions of contact lenses from 13.2 ± 1.1 ng mLâ1 to 15.4 ± 1.9 ng mLâ1 and from 21.3 ± 1.6 ng mLâ1 to 23.5 ± 1.5 ng mLâ1, respectively. In the artificial saliva in contact with baby teether samples only DEHP was found, from 4.91 ± 0.31 ng mLâ1 to 6.78 ± 0.23 ng mLâ1, with good recoveries ranging from 81.3 ± 8.4% to 106.3 ± 5.2%.
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Journal: Analytica Chimica Acta - Volume 985, 8 September 2017, Pages 69-78