کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5133091 1492051 2018 49 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antioxidant properties of catechins: Comparison with other antioxidants
ترجمه فارسی عنوان
خواص آنتی اکسیدانی کاتچین: مقایسه آنتی اکسیدان های دیگر
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Antioxidant properties of five catechins and five other flavonoids were compared with several other natural and synthetic compounds and related to glutathione and ascorbate as key endogenous antioxidants in several in vitro tests and assays involving erythrocytes. Catechins showed the highest ABTS-scavenging capacity, the highest stoichiometry of Fe3+ reduction in the FRAP assay and belonged to the most efficient compounds in protection against SIN-1 induced oxidation of dihydrorhodamine 123, AAPH-induced fluorescein bleaching and hypochlorite-induced fluorescein bleaching. Glutathione and ascorbate were less effective. (+)-catechin and (−)-epicatechin were the most effective compounds in protection against AAPH-induced erythrocyte hemolysis while (−)-epicatechin gallate, (−)-epigallocatechin gallate and (−)-epigallocatechin protected at lowest concentrations against hypochlorite-induced hemolysis. Catechins [(−)-epigallocatechin gallate and (−)-epicatechin gallate)] were most efficient in the inhibition of AAPH-induced oxidation of 2′7′-dichlorodihydroflurescein contained inside erythrocytes. Excellent antioxidant properties of catechins and other flavonoids make them ideal candidates for nanoformulations to be used in antioxidant therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 241, 15 February 2018, Pages 480-492
نویسندگان
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