کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5137119 1494533 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protein extract from the fruit pulp of Momordica dioica shows anti-diabetic, anti-lipidemic and antioxidant activity in diabetic rats
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Protein extract from the fruit pulp of Momordica dioica shows anti-diabetic, anti-lipidemic and antioxidant activity in diabetic rats
چکیده انگلیسی
Streptozotocin-induced diabetic rats were orally treated with protein extract from Momordica dioica fruit pulp for 30 days. Treated rats showed reduced blood glucose levels, greater oral carbohydrate tolerance, and ameliorated weight loss. Glucose, urea, triglycerides, cholesterol, low-density lipoprotein, alanine aminotransferase, and aspartate aminotransferase levels were significantly decreased, while high-density lipoprotein levels were significantly increased in treated diabetic rats, compared to untreated diabetic rats (P < 0.05). In liver and kidney tissues, superoxide dismutase, catalase, glutathione peroxidase, and reduced glutathione levels were significantly increased, while thiobarbituric acid reactive substance levels significantly decreased in treated diabetic rats, compared to untreated diabetic rats (P < 0.05). Furthermore, there were no significant morphological changes in the liver and kidney tissue of treated rats, compared to control rats. In this light, it has been established for the first time that protein extract from a non-bitter species of Momordica has anti-diabetic, anti-lipidemic, and antioxidant properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 33, June 2017, Pages 181-187
نویسندگان
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