کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137119 | 1494533 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Protein extract from the fruit pulp of Momordica dioica shows anti-diabetic, anti-lipidemic and antioxidant activity in diabetic rats
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
Streptozotocin-induced diabetic rats were orally treated with protein extract from Momordica dioica fruit pulp for 30Â days. Treated rats showed reduced blood glucose levels, greater oral carbohydrate tolerance, and ameliorated weight loss. Glucose, urea, triglycerides, cholesterol, low-density lipoprotein, alanine aminotransferase, and aspartate aminotransferase levels were significantly decreased, while high-density lipoprotein levels were significantly increased in treated diabetic rats, compared to untreated diabetic rats (PÂ <Â 0.05). In liver and kidney tissues, superoxide dismutase, catalase, glutathione peroxidase, and reduced glutathione levels were significantly increased, while thiobarbituric acid reactive substance levels significantly decreased in treated diabetic rats, compared to untreated diabetic rats (PÂ <Â 0.05). Furthermore, there were no significant morphological changes in the liver and kidney tissue of treated rats, compared to control rats. In this light, it has been established for the first time that protein extract from a non-bitter species of Momordica has anti-diabetic, anti-lipidemic, and antioxidant properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 33, June 2017, Pages 181-187
Journal: Journal of Functional Foods - Volume 33, June 2017, Pages 181-187
نویسندگان
Sundar Poovitha, Muddineni Siva Sai, Madasamy Parani,