کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137616 | 1494532 | 2017 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Encapsulation of anthocyanin in liposomes using supercritical carbon dioxide: Effects of anthocyanin and sterol concentrations
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
Anthocyanin-loaded liposomes were prepared via an improved supercritical carbon dioxide (SC-CO2) method. The effects of anthocyanin and cholesterol concentrations were studied in terms of the particle size distribution, encapsulation efficiency (EE), bioactive loading, morphology, zeta potential, anthocyanin-phospholipid interaction and in vitro release profiles. Anthocyanin-loaded liposomes had a particle size of 159 ± 0.2 nm, polydispersity index of 0.244 ± 0.02, EE of 50.6% and zeta potential of â40.2 mV. Elevated anthocyanin concentration increased the particle size with reduced uniformity due to enhanced electrostatic interactions and hydrogen bonding between anthocyanin and phospholipids. Liposomes exhibited unilamellar, spherical and near-spherical shapes with increased asymmetry and heterogeneity in the bilayer packing upon increased anthocyanin and cholesterol addition. The anthocyanin release from liposomes was slow (â¤35.9%) in the simulated gastric fluid but rapid in the simulated intestinal fluid, induced by the degradation of the vesicles by pancreatin. Anthocyanin-loaded liposomes show great potential for functional food and nutraceutical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 34, July 2017, Pages 159-167
Journal: Journal of Functional Foods - Volume 34, July 2017, Pages 159-167
نویسندگان
Lisha Zhao, Feral Temelli, Lingyun Chen,