Selective colorimetric analysis of spermine based on the cross-linking aggregation of gold nanoparticles chain assembly

Under a weak alkaline condition, chain assemblies of gold nanoparticles (AuNPs) were formed along calf thymus DNA (ctDNA) double strands. Then, a simple and colorimetric assay for spermine was proposed bases on the cross-linking aggregation of AuNPs assembly, which was highly stable, sensitive and selective.207