Molecularly imprinted solid phase extraction method for simultaneous determination of seven nitroimidazoles from honey by HPLC-MS/MS

In this work, a selective sample clean-up procedure that combined molecular imprinting technique and solid phase extraction was developed for different nitroimidazoles (NMZs) simultaneous extraction from honey samples. An off-line MISPE method followed by HPLC-MS-MS for simultaneous determination of seven NMZs from honey samples with precision and accuracy was established.98