Modern solutions in the field of microextraction using liquid as a medium of extraction

The monitoring of compounds present in samples at trace/ultra-trace level usually requires a preliminary step of isolation and/or enrichment of analytes. Against, sample preparation is considered as crucial part of whole analytical procedures, in particular in samples characterized by complex matrices composition. Several new miniaturized extraction techniques is introduced and extensively applied to different type of samples. Here you can highlight solid phase microextraction (SPME) and liquid phase microextraction (LPME). LPME was introduced to overcome drawbacks of liquid liquid extraction (LLE). Based on the recently published literature data, this review provides an update of the most important features and application of LPME. Comparison of these techniques have been made. Moreover, application of different type of LPME techniques for the extraction of different kind of materials such as biological, environmental, pharmaceutical and food was summarized.