In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N′-ethylenediamine bidentate ester ligands

Synthesis, characterization, stability, interactions with bovine serum albumin and ascorbic acid, in vitro anticancer activity, cell cycle and mode of cell death, as well as kinetics study and drug uptake of novel gold(III) complexes of general formula [AuCl2{(S,S)-R2eddl}]PF6, (R2eddl = O,O′-dialkyl-(S,S)-ethylenediamine-N,N′-di-2-(4-methyl)pentanoate; R = n-Pr, n-Bu, n-Pe, i-Bu) are presented.96