Sequence-specific fluorometric recognition of HIV-1 ds-DNA with zwitterionic zinc(II)-carboxylate polymers

Four water stable zwitterionic zinc carboxylate polymers are synthesized. The one-dimensional compound with rigid and planar 2,2′-bipyridyl ancillary ligand can interact with carboxyfluorescein labeled DNA to form an effective sensing platform for the detection of HIV ds-DNA with a 7.4 nM detection limit.216