New copper(I) complexes bearing lomefloxacin motif: Spectroscopic properties, in vitro cytotoxicity and interactions with DNA and human serum albumin

Herein we present lomefloxacin's derivative: aminomethyl(diphenyl)phosphine and its CuI or CuNCS complexes with diimine. High stability of the complexes in aqueous solutions in the presence of oxygen was proven. All complexes exhibit cytotoxicity (towards CT26, A549 MCF7 - cancer cell lines) higher than the toxicity of lomefloxacin and cisplatin.