Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model

Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 11, 1 June 2017, Pages 2594-2601

Nagarajan Muthukaman, Macchindra Tambe, Mahamadhanif Shaikh, Dnyandeo Pisal, Sanjay Deshmukh, Shital Tondlekar, Neelam Sarode, Lakshminarayana Narayana, Jitendra M. Gajera, Vidya G. Kattige, Srinivasa Honnegowda, Vikas Karande, Abhay Kulkarni,