کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5157218 | 1500589 | 2017 | 43 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibacterial and antioxidative activity of O-amine functionalized chitosan
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کلمات کلیدی
3-(4,5-dimethythiazol-2-yl)-2,5-diphenyltetrazolium bromideLB brothDMEMGlcNAcABTSEDADMSO - DMSOMTT - MTTpara-Benzoquinone - para-benzoquinoneROS - ROSEthylene diamine - اتیلن دیامینStaphylococcus aureus - استافیلوکوک اورئوسEscherichia coli - اشریشیا کُلیBacillus cereus - باسیلوس سرئوسDimethyl sulfoxide - دیمتیل سولفواکسیدPseudomonas aeruginosa - سودوموناس آئروژینوزاluria-bertani broth - سوپ لووریا برتانیChitosan derivatives - مشتقات کیتوزانReactive oxygen species - گونههای فعال اکسیژن
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cinnamaldehyde was immobilized to O-amine functionalized chitosan via a coupling reaction. Fourier transform infrared spectroscopy confirmed N-cinnamyl substitution. Wetting analyses demonstrate more hydrophobicity in the N-cinnamyl substituted O-amine functionalized chitosan compared to chitosan or unsubstituted O-amine functionalized chitosan. Thermal gravimetric analysis and differential scanning calorimetry demonstrates that the prepared N-cinnamyl substituted O-amine functionalized chitosan exhibits higher thermostability than unmodified chitosan at temperatures in which polysaccharides are commonly stored and utilised. The N-cinnamyl substituted O-amine functionalized chitosan, against four different bacteria strains [two gram-positive (Staphylococcus aureus and Bacillus cereus) and two gram-negative (Escherichia coli and Pseudomonas aeruginosa)], displays promotion of inhibition activity against these bacterial strains. Finally, the antioxidative activity of the N-cinnamyl substituted O-amine functionalized chitosan was compared with those activities of chitosan and O-amine functionalized chitosan. This was evaluated by uninhibited and inhibited hyaluronan degradation and ABTS assay. The N-cinnamyl substituted O-amine functionalized chitosan shows a lower activity towards donating a hydrogen radical compared to chitosan or O-amine functionalized chitosan. On the other hand, the N-cinnamyl substituted O-amine functionalized chitosan exhibited a higher ability to scavenge the ABTS+ cation radical compared to chitosan and O-amine functionalized chitosan.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 169, 1 August 2017, Pages 441-450
Journal: Carbohydrate Polymers - Volume 169, 1 August 2017, Pages 441-450
نویسندگان
Tamer M. Tamer, Mohamed A. Hassan, Ahmed M. Omer, KatarÃna Valachová, Mohamed S. Mohy Eldin, Maurice N. Collins, Ladislav Å oltés,