کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5157365 | 1500592 | 2017 | 23 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Gallium-modified chitosan/poly(acrylic acid) bilayer coatings for improved titanium implant performances
ترجمه فارسی عنوان
پوشش دو لایه کیتوزان / پلی (اکریلیک اسید) اصلاح شده گالیم برای بهبود عملکرد ایمپلنت تیتانیوم
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
چکیده انگلیسی
A gallium-modified chitosan/poly(acrylic acid) bilayer was obtained by electrochemical techniques on titanium to reduce orthopaedic and/or dental implants failure. The bilayer in vitro antibacterial properties and biocompatibility were evaluated against Escherichia coli and Pseudomonas aeruginosa and on MG63 osteoblast-like cells, respectively. Gallium loading into the bilayer was carefully tuned by the electrochemical deposition time to ensure the best balance between antibacterial activity and cytocompatibility. The 30Â min deposition time was able to reduce in vitro the viable cell counts of E. coli and P. aeruginosa of 2 and 3 log cfu/sheet, respectively. Our results evidenced that the developed antibacterial coating did not considerably alter the mechanical flexural properties of titanium substrates and, in addition, influenced positively MG63 adhesion and proliferation. Therefore, the gallium-modified chitosan/poly(acrylic acid) bilayer can be exploited as a promising titanium coating to limit bacterial adhesion and proliferation, while maintaining osseointegrative potential.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 166, 15 June 2017, Pages 348-357
Journal: Carbohydrate Polymers - Volume 166, 15 June 2017, Pages 348-357
نویسندگان
Maria A. Bonifacio, Stefania Cometa, Manuela Dicarlo, Federico Baruzzi, Silvia de Candia, Antonio Gloria, Maria M. Giangregorio, Monica Mattioli-Belmonte, Elvira De Giglio,