A new application of headspace single-drop microextraction technique for compound specific carbon isotopic determination of gasoline range hydrocarbons

► HS-SDME is an efficient extraction method for gasoline range hydrocarbons (GRH). ► This method has good reproducibility and causes no obvious isotopic fractionation of GRH. ► The ionic strength of working solutions and the injection split ratio have no evident effect on the δ13C values of GRH. ► The application proved that HS-SDME is a promising tool for determining δ13C values of GRH in oils.