Cytotoxic lanostane triterpenoids from the fruiting bodies of Piptoporus betulinus

Ten lanostane triterpenoids including five previously undescribed ones, piptolinic acids A−E, were isolated and identified from the fruiting bodies of Piptoporus betulinus. Piptolinic acid A exhibited moderate cytotoxic activity against HL-60 and THP-1 (IC50 = 1.77 and 8.21 μM, respectively).257