Chemical constituents from Melicope pteleifolia leaves

Five acetophenones bearing spiroketal-hexofuranoside rings (melicospiroketals A-E), one di-C-glycosidic acetophenone, and two benzopyrans, along with 16 known compounds were isolated from the leaves of Melicope pteleifolia. All the isolates were also evaluated for their neuraminidase inhibitory activities against H1N1, H9N2, wild-type H1N1 and oseltamivir-resistant H1N1 (H274Y mutation) virus strains.