Cytotoxic indole alkaloids from Tabernaemontana officinalis

Tabernaemontana officinalis alkaloids were elucidated as six dimeric indole alkaloids taberdivarines A-F (1-6) and two monomers taberdivarines G-H (7-8). Alkaloids 1-2 were the first reported voaphylline-vobasinyl type dimers, while 3-6 exhibited the cytotoxicity.