Limonoids from the fruits of Melia azedarach and their cytotoxic activities

► Thirty-one limonoids and a triterpenoid were isolated from Melia azedarach fruits. ► Fourteen were previously unrecorded in the literature. ► Meliarachin C and a salannin derivative induced apoptotic cell death in HL60 cells. ► Meliarachin C and a salannin derivative exhibited selective toxicity in leukemia cells.