Lumusidines A−D and villalstonidine F, macroline-macroline and macroline-pleiocarpamine bisindole alkaloids from Alstonia macrophylla

► Five bisindole alkaloids were isolated from the stem-bark extract of Alstonia macrophylla. ► Four are macroline-macroline bisindoles. ► One is a macroline-pleiocarpamine bisindole.