Oxygenated compounds from the bioconversion of isostevic acid and their inhibition of TNF-α and COX-2 expressions in LPS-stimulated RAW 264.7 cells

► Fourteen oxygenated compounds were obtained from the bioconversion of isostevic acid. ► Structures were elucidated by 2D NMR and HRMS. ► Four compounds were confirmed by X-ray crystallographic analyses. ► Several compounds exhibited anti-inflammatory activity.