Cytotoxic triterpenoids from Ganoderma lucidum

Six triterpenoids, together with 37 known compounds, were isolated from Ganoderma lucidum. Their structures were elucidated on the basis of spectroscopic studies and comparison with known related compounds. All of the compounds were assayed for their inhibitory activity against human HeLa cervical cancer cell lines. In addition, structure-activity relationships are discussed.