Cytotoxic tirucallane C26 triterpenoids from the stem barks of Aphanamixis grandifolia

From the stem barks of Aphanamixis grandifolia, five tirucallane type C26 triterpenoids and two known compounds were isolated. All isolates were evaluated for their cytotoxic activity against five tumor cell lines (MCF-7, HeLa, HepG2, SGC-7901 and BGC-823) in vitro.